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5,9,14 Yet, the increasing clinical relevance of nano- and micro-technologies in the past decades 20,21 has also promoted the development and use of novel stimuli-responsive platforms for therapeutic purposes, like superparamagnetic iron oxide nanoparticles (SPION)

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Despite its advantages, it’s important to acknowledge GHK-Cu’s limitations when compared to traditional acne treatments in a research context: Limited Direct Evidence for Active Acne Vulgaris: While it has anti-inflammatory properties, there is currently limited direct clinical evidence specifically demonstrating GHK-Cu as a primary treatment for active acne breakouts (e.g., reducing papules, pustules, or cysts)